Systemic Inflammatory Response Syndrome After Acute Myocardial Infarction Complicated by Cardiogenic Shock

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Systemic inflammatory response syndrome after acute myocardial infarction complicated by cardiogenic shock.

BACKGROUND The role of inflammation in patients with coronary artery disease is emerging. We sought to assess the profile and outcomes of patients with a clinical syndrome of severe systemic inflammation that led to a diagnosis of suspected sepsis in the setting of acute myocardial infarction complicated by cardiogenic shock (CS). METHODS Patients enrolled in the randomized SHOCK (SHould we e...

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Acute cardiomyocyte necrosis in the infarcted heart generates damage-associated molecular patterns, activating complement and toll-like receptor/interleukin-1 signaling, and triggering an intense inflammatory response. Inflammasomes also recognize danger signals and mediate sterile inflammatory response following acute myocardial infarction (AMI). Inflammatory response serves to repair the hear...

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Circulatory support in cardiogenic shock after acute myocardial infarction.

Mortality is high in patients with acute coronary failure and cardiogenic shock. The most commonly used device for hemodynamic support is the intra-aortic balloon, which, however, may be insufficient in patients with refractory cardiogenic shock. This is a case report of a patient complaining of two days of intense and oppressive chest pain, radiating to the left arm. The ECG showed ST elevatio...

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Cardiogenic shock complicating acute myocardial infarction.

Although numerous clinical complications are associated with the development of acute myocardial infarction (AMI), none are more potentially devastating or carry a worse prognosis than cardiogenic shock (CS). It’s the leading cause of death in patient hospitalized with AMI and continues to complicate between 5-8% of ST-elevation myocardial infarction (STEMI) and approximately 2.5% of non-ST-ele...

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ژورنال

عنوان ژورنال: Archives of Internal Medicine

سال: 2005

ISSN: 0003-9926

DOI: 10.1001/archinte.165.14.1643